Methylcobalamin and Gabapentin Tablet

Methylcobalamin and Gabapentin Tablet

74 INR/Box

Product Details:

  • Purity 98%
  • Formulations Type General Drugs
  • Formulations Form Tablets
  • Gender/Age Group Adult
  • Storage Instructions Dry Place
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Methylcobalamin and Gabapentin Tablet Price And Quantity

  • 74 INR/Box
  • 300 Box

Methylcobalamin and Gabapentin Tablet Product Specifications

  • Tablets
  • Dry Place
  • Adult
  • General Drugs
  • 98%

Methylcobalamin and Gabapentin Tablet Trade Information

  • Cash in Advance (CID) Cash Advance (CA)
  • 300 Box Per Month
  • 1 Months
  • Yes
  • Sample costs shipping and taxes has to be paid by the buyer
  • Western Europe Australia North America Eastern Europe Middle East Central America South America Asia Africa
  • All India

Product Description

Methylcobalamin and Gabapentin combination is useful for the treatment of neuropathic disorders or seizure disorders. Methylcobalamin is a form of vitamin B that is used to prevent postherpetic neuralgia, neuralgia intercostals, and diabetic neuropathy. Gabapentin is an anti-convulsant that prevents repeated electrical signals in the brain that cause seizures and is used to treat epilepsy or other similar disorders.
Gabapentin is used in combination with other antiseizure (anticonvulsant) drugs to manage partial seizures with or without generalization in individuals over the age of 12. Gabapentin can also be used to treat partial seizures in children between the ages of three and 12. Off-label uses (legal uses not specifically approved by the United States Food and Drug Administration [FDA]) include treatment of severe, chronic pain caused by nerve damage (such as occurs in shingles, diabetic neuropathy, multiple sclerosis, or post-herpetic neuralgia). Studies are also looking at using gabapentin to treat bipolar disorder (also known as manic-depressive disorder).
Some of the disorders that may be preventable or treatable with this natural vitamin therapy, called methylcobalamin, include chronic fatigue syndrome, Parkinson's disease, peripheral neuropathies, Alzheimer's disease, muscular dystrophy and neurological aging. Americans have immediate access to this unique and new form of vitamin B-12, and, unlike prescription drugs, it costs very little and is free of side effects. The most common form of vitamin B12 is called cyanocobalamin. However, over the last ten years, a number of central and peripheral neurological diseases have been linked to a deficiency of a very specific cobalamin, the methylcobalamin form, that is required to protect against neurological diseases and aging. The liver converts a small amount of cyanocobalamin into methylcobalamin within the body, but larger amounts of methylcobalamin are necessary to correct neurological defects and protect against aging.

Pharmacology:
Gabapentin [1-(aminomethyl)cyclohexane acetic acid] is a novel anti-epileptic agent, originally developed as a gamma-aminobutyric acid (GABA)-mimetic compound to treat spasticity, and has been shown to have potent anticonvulsive effects. Initially approved only for use in partial seizures, it soon showed promise in the treatment of chronic pain syndromes, especially neuro-pathic pain.

Pharmacokinetics:
Gabapentin, available only as oral preparations, is absorbed in the small intestine by a combination ofdiffusion and facilitated transport. Its transport from the gut following oral administration is facilitated by its binding to an, as yet unidentified, receptor linked to a saturable L-amino acid transport mechanism. As this carrier-dependent transport is saturable, the bioavailability of gabapentin varies inversely with dose.
Mecobalamin is the neurologically active form of vitamin B12 and occurs as a water-soluble vitamin in the body. It is a cofactor in the enzyme methionine synthase, which functions to transfer methyl groups for the regeneration of methionine from homocysteine. In anaemia, it increases erythrocyte production by promoting nucleic acid synthesis in the bone marrow and by promoting maturation and division of erythrocytes.

Contraindications:
Gabapentin is contraindicated in patients who have demonstrated hypersensitivity to the drug or its ingredients.

Side Effects:
Headache, Dizziness or drowsiness, Loss of coordination, Nausea or vomiting, Dry mouth or bad taste in the mouthStomach discomfort, diarrhea, or constipation, Blurred or disturbed vision, Swelling of the chest or breast area.

Storage:
Store at 25°C (77°F); excursions permitted to 15° - 30°C (59° - 86°F).
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